https://www.dunaieflab.org/home daily 1.0 2024-11-19 https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/355587b6-8fe0-4160-be56-de596477bc9e/2997+OS+10x+ZO1+edited+cropped.jpg Home https://www.dunaieflab.org/our-research daily 0.75 2024-04-17 https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/1579618786638-SGC2ICG36NA1PWHAO8KH/63xzm2_zm2.jpg Our Research - Iron. Iron is essential for life. In physiologic conditions, iron can accept or donate electrons, serving as a cofactor in chemical reactions as fundamental as DNA synthesis and energy metabolism. But iron’s very source of utility, is also its source of toxicity. Excess iron can trigger oxidative stress and cell death. For the past two decades we have studied the role of iron in age-related macular degeneration. To learn more head to pubmed via the link below or reach out directly though the contact us page. https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/1579618829083-YL9GGW0SOWRFQIDBPJJU/Samy2018.06_control1_ch00+copy.jpg Our Research - Inflammation. Iron is essential for life - in humans and bacteria. To combat bacterial invasion, eukaryotic cells sequester iron internally, starving extracellular pathogens of the iron necessary for survival. But what happens as we age, and chronic inflammation occurs without bacteria to fight? https://www.dunaieflab.org/our-team daily 0.75 2025-11-17 https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/7d76a0f2-7484-4f63-b92a-fe7db4a607a6/Josh+making+comment+at+Harvard+AMD+meeting+10-5-23.jpg https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/b3adb771-403d-4f1f-86b4-37368879c39b/photo+of+Tim+at+Poster+session+harvard+AMD+meeting+10-5-23.jpg https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/78eb8a3b-37ee-49be-8a33-ccccd0b62c27/Dunaief_lab_edited.jpg https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/3ff4e2fc-ee5e-4215-ba00-25a1129a631f/ARVO+gala+photo+10-5-23.jpg https://www.dunaieflab.org/contact daily 0.75 2022-07-15 https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/4592ec6a-8317-4939-acc8-c8d75015a554/Eyeron+lab+edited+-+white.png https://www.dunaieflab.org/the-dunaief-behind-dunaief-lab daily 0.75 2023-10-05 https://images.squarespace-cdn.com/content/v1/5e25f27a20684f527f0b23ac/1579629652440-PBJB4XRO6JLJQBDZ3J7J/Josh+playing+sax+with+Osler+Circle+Beatles+band.jpg Josh Dunaief https://www.dunaieflab.org/new-page daily 0.75 2020-01-20 https://www.dunaieflab.org/funding daily 0.75 2020-01-28